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Table 2 Subject characteristics relative to glioma grade, IDH mutation, and MGMT methylation

From: Beyond invasive biopsies: using VASARI MRI features to predict grade and molecular parameters in gliomas

a. Subject characteristics relative to glioma grade

 

Low Grade (n= 28)

High Grade (n= 79)

p-value

Sex (male)

14 (50%)

46 (58.22%)

0.451

Age (years)

33.32 (12.44)

50.35 (13.90)

 < 0.001*

Ki-67b

7.12 (13.61)

24.86 (19.09)

 < 0.001*

b. Subject characteristics relative to IDH mutation statusa

 

Mutant (n= 24)

Wildtype (n= 81)

p-value

Sex (male)

17 (70.83%)

42 (51.85%)

0.254

Age (years)

37.42 (10.54)

48.39 (15.99)

0.002*

Ki-67b

16.61 (18.01)

21.75 (19.86)

0.261

c. Subject characteristics relative to MGMT methylation status

 

Methylated (n= 30)

Unmethylated (n= 77)

p-value

Sex (male)

16 (53.33%)

44 (57.14%)

0.721

Age (years)

48.30 (11.4)

44.96 (16.71)

0.317

Ki-67b

15.14 (18.05)

22.32 (19.67)

0.087

  1. Chi-Squared Test and Independent Samples T-Test were utilized as appropriate. Data are presented as number (percentage) or mean (standard errors)
  2. IDH Isocitrate dehydrogenase, MGMT Methylguanine DNA‐methyltransferase
  3. *denotes statistically significant p value of less than 0.05
  4. adata missing (n = 2)
  5. bdata missing (n = 3)