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Fig. 5 | Cancer Imaging

Fig. 5

From: Beyond invasive biopsies: using VASARI MRI features to predict grade and molecular parameters in gliomas

Fig. 5

a Axial T1-weighted, (b) T2-weighted, (c) FLAIR, and (d) post-contrast administration T1-weighted MR images from a 40-year-old male with a WHO CNS Glioma Grade 4. Area of enhancement is visible that is less than 33% of the total area with pathological FLAIR signal intensity.The abnormal areas on T1 and FLAIR being approximately the same (expansive), as well as the enhancement having a vague and thin thickness. Despite the high-grade histopathological appearance, this glioma is IDH-mutant. It is predominantly solid with quite extensive non-enhancing area (68–100% of the total pathological area on FLAIR), accompanied by tumor and edema crossing the midline, and the overall large size of FLAIR abnormalities. This tumor was also proven to have methylation in its MGMT gene

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Cancer Imaging

ISSN: 1470-7330

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