3D analysis of apparent diffusion coefficient histograms in hepatocellular carcinoma: correlation with histological grade

Table 1 Histological grade of hepatocellular carcinoma, the parameters of ADC histograms, Pearson’s product moment correlation coefficient, and one-way ANOVA with the Tukey-Kramer post hoc test

	Well diff HCC	Mod diff HCC	Poor diff HCC	Pearson’s correlation coefficient	Pearson’s correlation coefficient P value	ANOVA Tukey-Kramer post hoc test
Mean	1051 ± 203	999 ± 163	964 ± 167	−0.141	0.301	n.s.
Standard deviation	180 ± 119	193 ± 86	227 ± 75	0.154	0.257	n.s.
Minimum	585 ± 388	411 ± 278	235 ± 102	−0.340	0.010*	0.009**
Maximum	1641 ± 558	1718 ± 571	1955 ± 704	0.156	0.252	n.s.
Mode	710 ± 517	881 ± 311	829 ± 319	0.074	0.588	n.s.
Skewness	0.58 ± 1.27	0.36 ± 0.88	0.50 ± 1.00	−0.011	0.936	n.s.
Kurtosis	4.75 ± 4.59	4.86 ± 3.14	5.37 ± 3.23	0.056	0.681	n.s.
5th percentile	822 ± 216	718 ± 178	642 ± 147	−0.268	0.046*	n.s.
50th percentile	1034 ± 198	992 ± 160	936 ± 154	−0.170	0.211	n.s.
75th percentile	1149 ± 258	1112 ± 181	1078 ± 187	−0.104	0.448	n.s.
90th percentile	1248 ± 293	1234 ± 223	1244 ± 244	−0.002	0.990	n.s.

Well diff HCC: Well differentiated hepatocellular carcinoma
Mod diff HCC: Moderately differentiated hepatocellular carcinoma
Poor diff HCC: Poorly differentiated hepatocellular carcinoma
*, ** P < 0.05
n.s. no significant difference
**Tukey-Kramer post hoc test: Well diff HCC vs Mod diff HCC, P = 0.521; Well diff HCC vs Poor diff HCC, P = 0.121; Mod diff HCC vs Poor diff HCC, P = 0.008

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