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Table 4 Variable patterns of uptake by PCC/PGL subtype

From: 68Ga-DOTATATE and 18F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity

 

Examples

SSTR PET

FDG PET

MIBG SPECT/PET

Pseudohypoxic

SDHx, VHL, HIF2

+++ a

+++

- (40 %) to ++

Kinase signalling

RET (MEN2), NF1, TMEM127, MAX

+ to ++

- or +

++ to +++

  1. amay diminish in small subgroup of patients with aggressive phenotype