Fig. 4From: 68Ga-DOTATATE and 18F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneityA 20Â year old male with SDHB germline mutation and metastatic PCC. Baseline Ga-68 DOTATATE (a) and F-18 FDG (b) demonstrated metastatic disease with a concordant pattern of uptake. The patient was treated with 3Â cycles of peptide receptor radionuclide therapy for uncontrolled hypertension. Follow-up DOTATATE and FDG imaging over a 2Â year period demonstrated stable findings (c: FDG at 2Â years). The high FDG-uptake was not predictive of an aggressive phenotype and reflects changes secondary to SDHB mutation and consequent disordered oxidative phosphorylationBack to article page