Table 5 Summary of key differences between abdominal neuroblastoma and Wilms tumour
From: Neuroblastoma and nephroblastoma: a radiological review
Parameter | Neuroblastoma | Wilms tumour |
|---|---|---|
Age | Younger age group: < 2Â years of age commonly | Slightly older age group : peak 3 - 4Â years of age |
Presentation | Painful abdominal mass | Painless abdominal mass |
Calcification | Calcification very common: 80-90% | Calcification uncommon: 10% |
Tumour composition | Solid mass lesion, rarely cystic components on US | Often cystic components at US |
Tumour margin | Poorly marginated mass that may extend up into chest | Well circumscribed mass - claw sign demonstrating it arises from the kidney |
Adrenal NBL displaces the kidney | ||
Vessel involvement | Encases vascular structures but does not invade them - elevates the aorta away from the vertebral column | Displaces adjacent structures – invades the vasculature with extension into renal vein/IVC |
Metastatic sites | Bone/bone marrow (common) | Lung (common) |
Liver | Liver | |
Lung/pleura | Local lymph nodes |