Table 1 INSS staging system [11]
From: Neuroblastoma and nephroblastoma: a radiological review
Tumour stage | Description |
|---|---|
Stage 1 | - Localized tumour with complete gross excision (+/-microscopic residual) |
- Ipsilateral lymph nodes negative for tumour | |
- Nodes attached to and removed with tumour may be positive | |
Stage 2A | - Localized tumour with incomplete gross excision |
- Ipsilateral non-adherent lymph nodes negative for tumour | |
Stage 2B | - Localized tumour +/- complete gross excision |
- Ipsilateral non-adherent lymph nodes positive for tumour | |
- Enlarged contralateral lymph nodes negative for tumour | |
Stage 3 | - Unresectable unilateral tumour infiltrating across midline |
- +/- Regional lymph node involvement | |
Stage 4 | - Any primary tumour with distant spread to lymph nodes, bone, bone marrow, liver, skin and/or other organs (except as defined for stage 4S) |
Stage 4S | - Only for infants <1Â year |
- Localized primary tumour with disseminated disease limited to skin, liver and/or bone marrow (marrow involvement < 10% on biopsy and MIBG negative marrow) |